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Dallas Observer: SMU, DOD Partner Again, This Time on Prosthetics That Feel

The Dallas Observer on its Unfair Park blog took note of the SMU-led Neurophotonics Research Center being funded by the Department of Defense and industry with a $5.6 million grant.

In the Sept. 13 entry, Journalist Robert Wilonsky explained details of the project to Observer readers and quoted Marc Christensen, electrical engineering chair in SMU’s Lyle School of Engineering.

“Enhancing human performance with modern digital technologies is one of the great frontiers in engineering. Providing this kind of port to the nervous system will enable not only realistic prosthetic limbs, but also can be applied to treat spinal cord injuries and an array of neurological disorders,” Christensen is quoted.

EXCERPT:
By Robert Wilonsky
SMU and the Department of Defense are already partners on that paper-thin camera straight outta 1984 by way of Minority Report. Now the Hilltop sends word of its latest DOD partnership — a $5.6-mil Neurophotonics Research Center that’ll be run by Marc Christensen, electrical engineering chair in SMU’s Lyle School of Engineering. Its charge: to develop prosthetic limbs using fiber optics that actually feel things like pressure and temperature. Says SMU: “Lightning-fast connections between robotic limbs and the human brain may be within reach for injured soldiers and other amputees.”

Read the full story.

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SMU leads $5.6M research center for fiber optic interface to link robotic limbs, human brain

DOD, industry fund $5.6 million SMU-led research center; Lyle School technology drives development of advanced prosthetics

Lightning-fast connections between robotic limbs and the human brain may be within reach for injured soldiers and other amputees with the establishment of a multimillion-dollar research center led by SMU engineers.

Funded by a Department of Defense initiative dedicated to audacious challenges and intense time schedules, the Neurophotonics Research Center will develop two-way fiber optic communication between prosthetic limbs and peripheral nerves.

This connection will be key to operating realistic robotic arms, legs and hands that not only move like the real thing, but also “feel” sensations like pressure and heat.

Successful completion of the fiber optic link will allow for sending signals seamlessly back and forth between the brain and artificial limbs, allowing amputees revolutionary freedom of movement and agility.

Potential to patch injured spinal cord

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Partners in the Neurophotonics Research Center also envision man-to-machine applications that extend far beyond prosthetics, leading to medical breakthroughs like brain implants for the control of tremors, neuro-modulators for chronic pain management and implants for patients with spinal cord injuries.

The researchers believe their new technologies can ultimately provide the solution to the kind of injury that left actor Christopher Reeve paralyzed after a horse riding accident. “This technology has the potential to patch the spinal cord above and below a spinal injury,” said Marc Christensen, center director and electrical engineering chair in SMU’s Lyle School of Engineering. “Someday, we will get there.”

The Defense Advanced Research Projects Agency (DARPA) is funding the $5.6 million center with industry partners as part of its Centers in Integrated Photonics Engineering Research (CIPhER) project, which aims to dramatically improve the lives of the large numbers of military amputees returning from war in Iraq and Afghanistan.

Currently available prosthetic devices commonly rely on cables to connect them to other parts of the body for operation — for example, requiring an amputee to clench a healthy muscle in the chest to manipulate a prosthetic hand. The movement is typically deliberate, cumbersome, and far from lifelike.

A link compatible with living tissue
The goal of the Neurophotonics Research Center is to develop a link compatible with living tissue that will connect powerful computer technologies to the human nervous system through hundreds or even thousands of sensors embedded in a single fiber.

Unlike experimental electronic nerve interfaces made of metal, fiber optic technology would not be rejected or destroyed by the body’s immune system.

“Enhancing human performance with modern digital technologies is one of the great frontiers in engineering,” said Christensen. “Providing this kind of port to the nervous system will enable not only realistic prosthetic limbs, but also can be applied to treat spinal cord injuries and an array of neurological disorders.”

The center brings together researchers from SMU, Vanderbilt University, Case Western Reserve University, the University of Texas at Dallas and the University of North Texas.

The Neurophotonics Research Center’s industrial partners include Lockheed Martin (Aculight), Plexon, Texas Instruments, National Instruments and MRRA.

Integrated system at cellular level
Together, this group of university and industry researchers will develop and demonstrate new increasingly sophisticated two-way communication connections to the nervous system.

Every movement or sensation a human being is capable of has a nerve signal at its root. “The reason we feel heat is because a nerve is stimulated, telling the brain there’s heat there,” Christensen said.

The center formed around a challenge from the industrial partners to build a fiber optic sensor scaled for individual nerve signals: “Team members have been developing the individual pieces of the solution over the past few years, but with this new federal funding we are able to push the technology forward into an integrated system that works at the cellular level,” Christensen said.

The research builds on partner universities’ recent advances in light stimulation of individual nerve cells and new, extraordinarily sensitive optical sensors being developed at SMU. Volkan Otugen, SMU site director for the center and Lyle School mechanical engineering chair, has pioneered research on tiny spherical devices that sense the smallest of signals utilizing a concept known as “whispering gallery modes.” A whispering gallery is an enclosed circular or elliptical area, like that found beneath an architectural dome, in which whispers can be heard clearly on the other side of the space.

Ultimate combination for two-way interface
The ultimate combination of advanced optical nerve stimulation and nerve-sensing technologies will create a complete, two-way interface that does not currently exist. “It will revolutionize the field of brain interfaces,” Christensen said.

“Science fiction writers have long imagined the day when the understanding and intuition of the human brain could be enhanced by the lightning speed of computing technologies,” said Geoffrey Orsak, dean of the SMU Lyle School of Engineering. “With this remarkable research initiative, we are truly beginning a journey into the future that will provide immeasurable benefits to humanity.”

A private university located in the heart of Dallas, SMU is building on the vision of its founders, who in 1911 imagined a distinguished center for learning emerging from the spirit of the city. Today, nearly 11,000 students benefit from the national opportunities and international reach afforded by the quality of SMU’s seven degree-granting schools. — Kimberly Cobb

SMU has an uplink facility located on campus for live TV, radio, or online interviews. To speak with Marc Christensen or to book a live or taped interview in the studio, call SMU News & Communications at 214-768-7650 or email news@smu.edu.

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USA Today on SMU Guildhall study: Video game review scores influence consumers

A three-day study by The Guildhall at SMU and Electronic Entertainment Design and Research (EEDAR) found that video game review scores influence consumers, at least to an extent.

The behavioral study was designed to measure the influence professional critic reviews have on purchase behavior, willingness to recommend, and consumer perception of individual video game titles. The results reinforce the industry’s assumptions of a strong causal link between professional critic reviews and their ability to affect consumers” actions and perceptions, said the study’s designers.

“Video games are increasingly contributing to the overall health of the entertainment sector, so it’s crucial to understand behavior,” said Jesse Divnich, vice president of analyst services for EEDAR. “The study findings clearly indicate that properly leveraging game reviews to form a positive anchoring effect can dramatically increase consumer’s perception, adoption and willingness to recommend a game title.”

During the three-day study that took place at the SMU campus in late March, 188 participants were asked to play a 20 minute session of the game Plants vs. Zombies. Each participant was randomly placed into one of three groups and asked to read an informational packet about Plants vs. Zombies before playing. All the information within the packets was identical except that one packet had high critic reviews of the game, the second had low reviews of the game, and the third (control) group had no reviews of the game at all.

USA Today in the July 8 article “Survey says video game review scores affect consumer behaviors” quoted the makers of the game: “We’ve always known that good reviews are beneficial to a game’s sales, but we didn’t realize just how significant a role they play in the purchasing decision process,” said Garth Chouteau of PopCap Games, makers of Plants vs. Zombies, in a statement on the study.

EXCERPT:

Video game review scores influence consumers — to an extent, according to a new study by EEDAR (Electronic Entertainment Design and Research) and The Guidhall at SMU.

Those shown high review scores for the game Plants vs. Zombies before playing the game tended to give the game a lower score than the review scores afterwards. Those given lower review scores prior to playing the game responded by giving the game higher scores than those shown to them.

However, those shown the higher review scores were twice more likely to take a boxed copy of the game instead of $10 cash. They were also 40% more likely to recommend the game to a friend than the low review groups.

Read the full story

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Research could change course of treatment for cancer that spreads to bones

New research holds promise for the thousands of people whose cancer has spread to their bones.

A common treatment for such patients is radiation surgery &#8212 even though very little is known about radiosurgery’s impact on bone strength, says Edmond Richer, associate professor of engineering at Southern Methodist University in Dallas.

Researchers now hope to conclusively establish the effects of radiation on human bone under a $596,000 grant from the National Institutes of Health. The 15-month grant will look at cervical fractures that sometimes occur six to eight months after stereotactic radiosurgery, called SRS, in patients with vertebral metastases.

SMU and UT Southwestern partnership
The researchers include Richer, the Robert C. Womack Endowed Chair of mechanical engineering and founder of the Biomedical Instrumentation and Robotics Laboratory in SMU’s Bobby B. Lyle School of Engineering, and Paul Medin, John Anderson and Joseph Zerwekh, professors at UT Southwestern Medical Center at Dallas.

The grant from NIH’s Neurological Disorders and Stroke Institute could transform treatment for patients with cancer metastases in the bone, as well as for millions with other bone diseases, such as osteoporosis, Richer says. According to the American Osteoporosis Foundation, an estimated 10 million Americans have the disease and 34 million more are at risk of developing it.

High fracture rate post-radiosurgery
Vertebral metastases occur in approximately 100,000 cancer patients annually, most of whom have major lung, breast, prostate, renal and myeloma malignancies, Richer says. SRS, considered a noninvasive procedure for treating spinal tumors, requires highly sophisticated instruments that deliver a precise amount of radiation to the targeted lesion.

A fracture rate of up to 39 percent has been reported in post-radiosurgery patients who receive high doses of radiation. The potentially devastating consequences of fractures include disabling pain, limited mobility and incontinence, Richer says.

“It’s a growing concern for radiology oncologists because there’s not much that can be done medically to reverse those problems,” he says, noting that advances in SRS technology outpace the research on its complex effects on bone.

“We began looking at the history of radiosurgery, and as algorithms and instruments have become more refined in the computation of doses and the delivery of radiation, the number of required treatments has decreased to a single procedure,” he says. “The issue of what happens to bone strength when the treatment goes from six lower-grade doses, each a month apart, to a single high-grade dose is an area practically void of research over the past 30 years.”

Gauging mechanical strength of bone
Richer’s focus for the project is on gauging the mechanical strength of bone and how it is affected. Assisting him is Julie Pollard, an SMU engineering graduate student, and Jessica Steinmann-Hermsen, a senior majoring in mechanical engineering and math.

“We’re looking at nondestructive modalities to determine bone strength,” specifically ultrasound technology, says Richer. While a bone mineral density test provides an accurate picture of calcium and other minerals in a segment of bone, it doesn’t measure the actual strength of the bone, he says.

Builds on earlier ultrasound instrument research
The project builds on Richer’s previous research to develop an ultrasound instrument that determines the elasticity of human bone. The instrument is under review by the U.S. Food and Drug Administration.

An abstract of the research by Richer and his collaborators has been accepted by the Acoustical Society of America, an international scientific society for sound-related fields, including biomedical ultrasound, for presentation at its biannual meeting in November. “Reduction of Ultrasound Propagation Velocity in Porcine Vertebrae Following Stereotactic Radiosurgery” was also selected for oral presentation at the meeting.

Richer supports interdisciplinary collaboration on research in medical robotics and advanced imaging techniques.

“Successful research is the result of free communication and thinking,” he says. “When engineers and physicians come together to discuss seemingly crazy ideas, frequently it turns out they’re not. And bringing them to fruition can help people in ways that neither the engineers nor the physicians imagined by themselves.” &#8212 Patricia Ward

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Africa’s cell phone boom can’t trump dire need for schools, roads, power, water

The fast-growing use of cell phones in Africa — where many people lack the basic human necessities — has made headlines worldwide the past few years.

The surprising boom has led to widespread speculation — and hope — that cell phones could potentially transform the impoverished continent.

But new research by economists Isaac M. Mbiti and Jenny C. Aker finds that cell phones — while a useful and powerful tool for many people in Africa — cannot drive economic development on their own.

Mbiti, at Southern Methodist University in Dallas, and Aker, at Tufts University in Medford, Mass., say that while there is evidence of positive micro-economic impacts, so far there’s limited evidence that mobile phones have led to macro-economic improvements in African countries.

Not a magic bullet
Cell phones can do only so much, say the researchers.

Many Africans still struggle in poverty and still lack reliable electricity, clean drinking water, education or access to roads.

“It’s really great for a farmer to find out the price of beans in the market,” says Mbiti, who has seen the impact of the cell phone boom firsthand while conducting research in his native Kenya. “But if a farmer can’t get the beans to market because there is no road, the information doesn’t really help. Cell phones can’t replace things you need from development, like roads and running water.”

Mbiti and Aker will publish their findings in the article “Mobile Phones and Economic Development in Africa” in the Journal of Economic Perspectives. The Washington, D.C.-based Center for Global Development, an independent nonprofit policy research organization, has published a working version of the paper online.

Needed: Infrastructure, policies, research

To really have an impact, say Mbiti and Aker, the cell phone boom requires complementary access to public infrastructure, such as reliable electricity.

“Also needed are appropriate policies and regulations that can promote the development of innovative mobile phone-based applications such as mobile banking services that have the potential to positively impact the economic livelihood of Africans,” Mbiti says.

The researchers also cite areas where more research is needed, such as the number of direct and indirect jobs created by the cell phone industry; whether mobile phones actually drive increases in gross domestic product; accurate mobile phone penetration rates; and whether cell phones are driving consumer surpluses due to increased market competition.

While there are some limited assessments of the impact by economists — in Niger, Uganda and rural South Africa, for example — more research by economists is needed, say Mbiti and Aker. They hope their study will spur economists to delve deeper into the long-term impact.

Boom improves daily life
Despite the extreme poverty of many Africans, mobile phone coverage has jumped from 10 percent of the population in 1999 to 60 percent in 2008, say Mbiti and Aker. Mobile phone subscriptions have skyrocketed from 16 million in 2000 to 376 million in 2008, they say.

As a result, cell phones have had some dramatic effects, particularly in rural Africa, say the researchers: farmers can compare market prices for the grain they grow; fisherman are able to sell their catch every day and reduce spoilage and waste by locating customers; health workers remind AIDS patients to take their daily medicine; day laborers find job opportunities; Africans have an affordable way to easily and quickly transfer money; health clinics can collect, measure, monitor and share health data; families share news of natural disasters, conflicts and epidemics; people learn to read and write to send text messages; election campaigns are monitored to prevent cheating; and new jobs are being created, such as small shops that sell, repair and charge cell phone handsets, as well as sell pre-paid phone credits.

Cell phones too costly for many Africans
But extreme poverty means cell phones remain out of reach for many Africans, say the researchers.

In some countries, for example, as few as 2 percent of the population can get access to a cell phone, say Mbiti and Aker.

In Niger the cost of a one-minute call can run 38 cents a minute — 40 percent of a household’s daily income. The cheapest mobile phone available costs the equivalent of enough millet to feed a family of five for five days. About 300 million Africans live on less than $1 a day, and 120 million live on less than 50 cents a day, say the researchers.

Critical infrastructure lacking
One impediment is the lack of adequate infrastructure. A fast-growing mobile phone company in Nigeria, for example, struggled to maintain electricity to the 3,600 base stations that communicate its cellular signals, they say. Ultimately the company kept the mobile towers operational by deploying its own generators — which burned 450 liters of diesel a second.

In sub-Saharan Africa, say the researchers, only 29 percent of roads are paved, and barely 25 percent of people have access to electricity. While it’s efficient for a manufacturer to take customer orders via mobile phone, their production is limited by the lack of a reliable power source and access to markets.

Mbiti is an assistant professor of economics in SMU’s Department of Economics. He is a 2010-2011 MLK Visiting Professor at Massachusetts Institute of Technology. Aker is assistant professor of development economics, Fletcher School and Department of Economics at Tufts. She is also a non-resident fellow, Center for Global Development, Washington, D.C.

SMU is a private university in Dallas where nearly 11,000 students benefit from the national opportunities and international reach of SMU’s seven degree-granting schools.