Wise, P-gp, P-glycoprotein, SMU

Drugs behave as predicted in computer model of key protein, enabling cancer drug discovery

Drugs important in the battle against cancer responded the way they do in real life and behaved according to predictions when tested in a computer-generated model of one of the cell’s key molecular pumps — the protein P-glycoprotein, or P-gp.

Biologists at SMU developed the computer generated model to overcome the problem of relying on only static images for P-gp’s structure, said biologist John G. Wise, lead researcher. Continue reading

P-gp, p-glycoprotein, prostate, cancer, Vogel, SMUResearchers discover new drug-like compounds that may improve odds for men battling prostate cancer. Continue reading →
Nova, neutrinos, Fermilab, SMU, CoanFermilab experiment observes change in neutrinos from one type to another over 500 miles. Continue reading →
Siberia 150x120Large genome-scale study finds Native American ancestors arrived in single migration wave. Continue reading →
SMU STEMPREP, Charles Knibb$3.78 million awarded by Department of Defense to SMU STEM project for minority students. Continue reading →

Earlier Research News

  • Top Quark: New precise particle measurement improves subatomic tool for probing mysteries of universe September 28, 2015
  • SMU Tower Center, Latino Center for Leadership Development create new strategic policy institute September 16, 2015
  • SMU’s Deason Institute for Cyber Security and Raytheon partner for strategic cyber research August 24, 2015
  • SMU Lyle School’s Delores Etter named to prestigious ‘100 Inspiring Women in STEM’ list August 24, 2015
  • SMU chemist Nicolay Tsarevsky wins prestigious National Science Foundation Career Award August 11, 2015
  • Mustang Minute! Simmons researcher tests if video game motion capture can teach math July 21, 2015
  • Kennewick Man: genome sequence of 8,500-year-old skeleton solves scientific controversy June 18, 2015
  • At peak fertility, women who desire to maintain body attractiveness report they eat less June 1, 2015
  • SMU conference promotes technology, economics of geothermal production in oil and gas fields May 15, 2015
  • SMU seismology team to cooperate with state, federal scientists in study of May 7 Venus, Texas earthquake May 8, 2015
  • James Brooks awarded high honor from American Association of Petroleum Geologists May 1, 2015
  • 1st proton collisions at the world’s largest science experiment expected to start the first or second week of June April 28, 2015
  • Most likely cause of 2013-14 earthquakes: Combination of gas field fluid injection, removal April 21, 2015
  • Physicists tune Large Hadron Collider to find “sweet spot” in high-energy proton smasher April 14, 2015
  • SMU’s engineering students to test new virtual reality game to practice solving hands-on infrastructure failure problems April 9, 2015
  • SMU geothermal scientist Maria Richards to guide global energy organization March 19, 2015
  • Why firms prefer not to disclose product quality — and how regulators might respond February 12, 2015
  • $2.5 million awarded to Retina Foundation and SMU Lyle to study macular degeneration January 29, 2015
  • Data-driven assessment ranks U.S. Metropolitan Areas by arts and cultural assets January 29, 2015
  • Bitcoin scams steal at least $11 million in virtual deposits from unsuspecting customers January 27, 2015
  • • View all research news →