NCI grant funds SMU research into cancer-causing viruses that hide from the immune system

SMU Department of Biological Sciences

NCI grant funds SMU research into cancer-causing viruses that hide from the immune system

cancer-causing virus, HTLV-1, HPV, human papilloma, human T-cell leukemia, SMU, HarrodGenes common to both the human T-cell leukemia virus and high-risk human papillomaviruses activate survival mechanisms in cancer cells. An SMU lab, with National Cancer Institute funding, is hunting ways to inhibit those genes to halt the development of cancer.

SMU biochemists, students probe membrane proteins that thwart cancer chemotherapies

Each semester, SMU biology professors Pia Vogel and John Wise welcome a handful of dedicated and curious students to their lab in the SMU Dedman Life Sciences building. The SMU undergraduate students and Dallas-area high school students get hands-on experience working on cancer research in the combined SMU Department of Biological Sciences laboratories of Wise and Vogel.

SMU 2015 research efforts broadly noted in a variety of ways for world-changing impact

SMU scientists and their research have a global reach that is frequently noted, beyond peer publications and media mentions. It was a good year for SMU faculty and student research efforts. Here's a small sampling of public and published acknowledgements during 2015, ranging from research modeling that made the cover of a scientific journal to research findings presented as evidence at government hearings.

Drugs behave as predicted in computer model of key protein, enabling cancer drug discovery

Wise, P-gp, P-glycoprotein, SMUDrugs important in the battle against cancer responded the way they do in real life and behaved according to predictions when tested in a computer-generated model of one of the cell’s key molecular pumps — the protein P-glycoprotein, or P-gp. Biologists at SMU developed the computer generated model to overcome the problem of relying on only static images for P-gp's structure, said biologist John G. Wise, lead researcher.

Researchers discover new drug-like compounds that may improve odds for men battling prostate cancer

P-gp, P-glycoprotein, prostate, cancer, SMU, VogelResearchers at Southern Methodist University, Dallas, have discovered three new drug-like compounds that could ultimately offer better odds of survival to prostate cancer patients. The drug-like compounds can be modified and developed into medicines that target a protein in the human body that is responsible for chemotherapy resistance in cancers, said biochemist Pia D. Vogel.

Prevention: Is Organic Food Really Better For You?

Prevention Bauer Chhabra organic fruit flyHealth and science reporter Richard Laliberte with Prevention Magazine has covered research carried out in the fruit fly lab of SMU biologist Johannes H. Bauer. The research by Plano, Texas high school student Ria Chhabra is featured in the article, "Is Organic Food Really Better For You?," published Aug. 21.

The Sydney Morning Herald: Flying in the face of the organic debate

Sydney Herald, Bauer, Chhabra, SMU, fruit flies, organicLife & Style reporter Sarah Berry with The Sydney Morning Herald has covered research carried out in the fruit fly lab of SMU biologist Johannes H. Bauer by Plano, Texas, high school student Ria Chhabra. The article published April 25, "Flying in the face of the organic debate."

New York Times: Is Organic Better? Ask a Fruit Fly

15well_fly-articleInlineNew York Times reporter Tara Parker-Pope has covered research carried out in the fruit fly lab of SMU biologist Johannes H. Bauer. The article on the New York Times Wellness blog covers the research of Bauer and Plano, Texas, high school student Ria Chhabra. It appeared April 17, "Is Organic Better? Ask a Fruit Fly."

Le Journal de la Science: Et si manger bio était bel et bien meilleur pour la santé?

Bauer, Chhabra, SMU, biology, fruit flies, organicScience journalist Alain Tranet writing in the Paris-based science publication Le Journal de la Science has covered research carried out in the fruit fly lab of SMU biologist Johannes H. Bauer by Plano, Texas, high school student Ria Chhabra. The article, "Et si manger bio était bel et bien meilleur pour la santé?," published April 3.

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