Drugs important in the battle against cancer responded the way they do in real life and behaved according to predictions when tested in a computer-generated model of one of the cell’s key molecular pumps — the protein P-glycoprotein, or P-gp.
The drug-like compounds can be modified and developed into medicines that target a protein in the human body that is responsible for chemotherapy resistance in cancers, said biochemist Pia D. Vogel. Continue reading
SMU now has a powerful new tool for research – one of the fastest academic supercomputers in the nation – and a new facility to house it.
With a cluster of more than 1,000 Dell servers, the system’s capacity is on par with high-performance computing (HPC) power at much larger universities and at government-owned laboratories. The U.S. Department of Defense awarded the system to SMU in August 2013. Continue reading
The article, “Long-Lost Letters Shed New Light on 19th-Century Bone Wars,” was published in the January 2013 issue of Earth. Continue reading
The science magazine Discover has covered the research of SMU vertebrate paleontologist Louis L. Jacobs and the infamous Bone Wars of the late 1800s.
In a post on Discover’s “80 beats” blog, the magazine reprinted the translation of a poem written by frontier naturalist and fossil hunter Jacob Boll. Jacobs came across the poem at the American Museum of Natural History on a label on the back of Eryops specimen No. AMNH 4183. Continue reading
Jason Heid, an editor with D Magazine’s popular Frontburner blog, covered the research of SMU vertebrate paleontologist Louis L. Jacobs and the infamous Bone Wars of the late 1800s.
The Bone Wars refers to a flurry of fossil speculation across the American West escalated into a high-profile national feud. Drawn into the spectacle were two scientists from the Lone Star State, geologist Robert T. Hill, now acclaimed as the Father of Texas Geology, and naturalist Jacob Boll, who made many of the state’s earliest fossil discoveries. Continue reading
In the late 1800s, furious fossil speculation across the American West escalated into a high-profile national feud called the Bone Wars. Vertebrate paleontologist Louis L. Jacobs unveils how the Bone Wars touched Texas through the lives of two Lone Star scientists, geologist Robert T. Hill and naturalist Jacob Boll. Continue reading
A picture is worth 1,000 words when it comes to understanding how things work, but 3D moving pictures are even better. That’s true for scientists trying to stop cancer by better understanding the proteins that make some chemotherapies unsuccessful. Now SMU biochemist John G. Wise at SMU has brought to life in a moving 3D computer model the structure of a key protein related to recurring cancers. Continue reading