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New power generation technology using waste heat from geothermal plants tested by SMU

The Geothermal Laboratory at Southern Methodist University (SMU) has just completed a research project that aims to use ultra-low-grade heat (150 °F to 250 °F) normally discarded by geothermal facilities to generate additional electricity. A central component of this project was the proprietary bottoming cycle technology of PwrCor, Inc., an advanced technology company that focuses on renewable energy solutions for Waste-to-Heat Power, Geothermal, and Solar markets.

Maria Richards

SMU’s Geothermal Laboratory, which is a research facility devoted to broadening the understanding and use of geothermal energy, compiled information such as ambient air temperature, injection temperature, and injection flow rate to quantify the total thermal energy within the spent geothermal fluids already being produced, but not utilized, by 31 of 73 U.S.-based geothermal sites for which data was available. What they found was that roughly 427 MWe can be generated from the spent geothermal fluids of currently existing facilities. This represents about 15% of the capacity of the sites looked at in the study.

“Geothermal energy is the work-horse of green power production.  Unlike various others, it operates 24/7, is suitable for baseload power supply, occupies a small footprint, and is designed to last,” noted Maria Richards, Geothermal Lab Coordinator for the Geothermal Laboratory. “PwrCor is working to improve the efficiency of our geothermal power infrastructure, and we commend their efforts.”

PwrCor is currently working with companies in the fuel cell and reciprocating engines industries, but they are also involved in initiatives in geothermal, oil and gas, and solar thermal. Their technology that allows for the cost-effective conversion of low-grade and ultra-low-grade heat to mechanical power and electricity could be revolutionary for businesses that could convert wasted heat to additional electrical power.

Joe Batir, a research geologist for the Geothermal Laboratory at SMU, said, “There is a great deal of heat being underutilized in geothermal power generating facilities around the United States.  Technology that can convert even a small portion of this underutilized heat into additional power has the potential of bringing major benefits to both geothermal power producers and to the environment.”– Globe News Wire and SMU

SMU’s research was featured in Think Geoenergy.

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SMU’s catalog of North Texas earthquakes confirms continuing effects of wastewater disposal

A comprehensive catalog of earthquake sequences in Texas’s Fort Worth Basin, from 2008 to 2018, provides a closer look at how wastewater disposal from oil and gas exploration has changed the seismic landscape in the basin.

In their report published in the Bulletin of the Seismological Society of America, Louis Quinones and Heather DeShon of Southern Methodist University (SMU) and colleagues confirmed that seismicity rates in the basin have decreased since 2014, a trend that appears to correspond with a decrease in wastewater injection.

However, their analysis also noted that new faults have become active during this period, and that seismicity continues at a greater distance from injection wells over time, suggesting that “far-field” changes in seismic stress will be important for understanding the basin’s future earthquake hazard potential.

“One thing we have come to appreciate is how broadly injection in the basin has modified stress within entire basin,” said DeShon.

The first thing researchers noted with wastewater injection into the basin “was the reactivation of individual faults,” she added, “and what we’re now starting to see is essentially the leftover energy on all sorts of little faults being released by the cumulative volume that’s been put into the basin.”

The earthquake catalog published in BSSA reported all seismicity recorded by networks operated by SMU between 2008 and 2018. Some seismic sequences in the catalog–such as the 2008 Dallas Fort Worth Airport earthquakes–are well-known and well-studied, while others such as the 2018 west Cleburne sequence are reported in the paper for the first time.

DeShon said publishing the complete catalog was important in part to help people recognize that “there are earthquakes throughout the basin, not just on these three or four sequences that have garnered a lot of press attention.”

The researchers found that overall seismicity in the Fort Worth Basin has been strongly correlated in time and space with wastewater injection activities, with most seismicity occurring within 15 kilometers of disposal wells.

Wastewater disposal volume began to decrease from its peak in 2014, mostly as a result of lower oil and gas prices, and the study showed “tapering off of seismicity along the faults that were near high-injection wells,” said Quinones.

There are exceptions to this pattern, including the 2015 Irving-Dallas and 2017 Lake Lewisville sequences that have no wells within 15 kilometers.

Induced earthquakes occur when wastewater injected back into the ground increases the pore pressure within the rocks and affects stress along faults in surrounding rock layers. In the Fort Worth Basin, these stress changes may propagate far–more than 10 kilometers–from the injection wells, the researchers suggested.

“Injection rates peaked in 2014, but we still don’t understand how spatially extensive the modification of pore pressure is at depth, so we still don’t understand how the hazard is going to reduce with time,” said DeShon.

There are still far fewer induced earthquakes in the Fort Worth Basin compared to regions such as Oklahoma, which also has experienced a dramatic increase in seismicity in the past decade as the result of wastewater disposal from oil and gas production. The volumes of injected wastewater are much higher in Oklahoma, and the faults there tend to be much closer together, DeShon said.

By contrast, Quinones said, faults in the Fort Worth Basin are more widely spaced, and there are few instances of earthquakes jumping between faults.

However, the dense population of the Dallas-Fort Worth metropolitan area makes it critical to continue monitoring the region’s induced earthquake risk, comparing seismic data with more information on wastewater injection.

For the moment, DeShon said, researchers only have access to monthly cumulative volume and average pressure at injection wellheads, in a report that is updated once a year.

“It would be best if injection data were provided in a more timely fashion in Texas, and if more detailed daily information on injection rates and  volumes and some measurements of downhole pressure were provided,” she said.–Seismological Society of America

About SMU

SMU is the nationally ranked global research university in the dynamic city of Dallas. SMU’s alumni, faculty and nearly 12,000 students in seven degree-granting schools demonstrate an entrepreneurial spirit as they lead change in their professions, communities and the world.

 

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Health & Medicine Researcher news SMU In The News Subfeature

Long exposure to protein inhibitor may be the key to more effective chemotherapy for treatment-resistant cancers, SMU finds

SMU researchers find success in treating drug-resistant prostate cancer cells in the lab

DALLAS (SMU) – Researchers at SMU’s Center for Drug Discovery, Design and Delivery (CD4) have succeeded in lab testing the use of chemotherapy with a specific protein inhibitor so that the chemotherapeutic medication is better absorbed by drug-resistant cancer cells without harming healthy cells. The approach could pave the way for a more effective way to treat cancers that are resistant to treatment.

A mix of drugs is frequently used to shrink cancer tumors or keep tumor cells from spreading to other parts of the body. But chemotherapy is so toxic that the mix often kills healthy cells, too, causing dreadful side effects for cancer patients. And eventually, many cancers learn how to resist chemotherapy, making it less effective over time.

“When multidrug resistance evolves, this leaves the patient with a very poor prognosis for survival and the oncologist with few, if any, effective tools, such as chemotherapy medicines, to treat what is very likely an aggressive and/or metastatic cancer at this point,” said John Wise, associate professor in the SMU Department of Biological Sciences and co-author of a study on the findings published Friday in PLOS One.

Much of the research led by CD4 director Pia Vogel and Wise is centered on a class of proteins called ABC transporters, a key factor in why many cancers resist chemotherapy.

Long exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMU

“These transporters are defensive proteins and are normally very, very good for us. They protect us from toxic chemicals by literally pumping them out of the cell, almost like a sump pump removes water from one’s cellar,” Vogel said.

But when someone has cancer, these proteins do more harm than good.

“One protein, P-glycoprotein, can pump nearly all chemotherapeutics out of the cancer cell, thereby making the cancer resistant to many drugs and untreatable,” Wise noted.

For this reason, SMU researchers tested the combination of using an inhibitor that temporarily shuts down P-glycoprotein’s ability to remove drugs from the cancer cells along with chemotherapeutics on prostate cancer cells grown in the lab, which have been shown to be resistant to multiple chemotherapeutic drugs.

The SMU team was able to show that if inhibitors of P-glycoprotein are used during and after the multidrug resistant cancer cells have been exposed to the chemotherapy drugs, then the cancer cells become much more sensitive to the chemotherapeutics.

The recipe for success was giving cancer cells a dose of both chemotherapy drugs and the P-gp inhibitor for two hours. Researchers then washed the prostate cancer cells to get rid of any residual chemotherapy drugs before giving the cells another dose of just P-gp inhibitor for 22 hours, lead author and SMU Ph.D. doctoral candidate Amila K. Nanayakkara explained.

Pia Vogel and John Wise

Prostate cancer cells that were given this treatment were shown to retain chemotherapy drugs at a much higher level compared to cancer cells not treated with the P-glycoprotein inhibitor. And after about 24 hours, much fewer of these cancer cells survived in this treatment compared to the cells which had not seen the inhibitor.

When the same tests were performed on normal noncancerous cells, “there was no sign of extra toxicity to the healthy cells using this method,” Wise added.

One issue, though, is how to duplicate this method in a patient’s body. “Once you’ve taken a chemotherapy drug, it’s not easy to remove it after just two hours,” said co-author Vogel, a professor in the SMU Department of Biological Sciences.

Still, the researchers argued that it is worth further research, because there are currently few options for cancer patients once their disease becomes resistant to multiple chemotherapies.

“Our paper shows these remarkable effects when the inhibitor is present during, and importantly, after exposure to chemotherapeutic,” Wise said. “And while ‘washing’ is not feasible in humans, the kidneys and other organs are in a sense doing the washing step for a patient. These organs are washing the chemotherapy from the bloodstream and therefore, out of cancer cells. So in that way, we think our preliminary cell culture studies may be translatable at least in principle to animals and people.”

News MedicalDallas Innovates and others wrote about the new research.

About SMU

SMU is the nationally ranked global research university in the dynamic city of Dallas. SMU’s alumni, faculty and nearly 12,000 students in seven degree-granting schools demonstrate an entrepreneurial spirit as they lead change in their professions, communities and the world.

 

 

 

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DNA from 31,000-year-old human teeth reveals new ethnic group living in Siberia during last Ice Age

An international team of researchers, including SMU anthropologist David Meltzer, discovered a new group of ancient Siberians. The research was published June 5, 2019 as a story in Nature

Two children’s milk teeth buried deep in a remote archaeological site in north eastern Siberia have revealed a previously unknown group of people lived there during the last Ice Age.

The finding was part of a wider study, which also discovered 10,000 year-old human remains in another site in Siberia are genetically related to Native Americans – the first time such close genetic links have been discovered outside of the US.

The two 31,000-year-old milk teeth found at the Yana Rhinoceros Horn Site in Russia which led to the discovery of a new group of ancient Siberians. Photo credit: Russian Academy of Sciences.

The international team of scientists, led by Professor Eske Willerslev who holds positions at St John’s College, University of Cambridge, and is director of The Lundbeck Foundation Centre for GeoGenetics at the University of Copenhagen, have named the new people group the ‘Ancient North Siberians’ and described their existence as ‘a significant part of human history’.

The DNA was recovered from the only human remains discovered from the era – two tiny milk teeth – that were found in a large archaeological site found in Russia near the Yana River. The site, known as Yana Rhinoceros Horn Site (RHS), was found in 2001 and features more than 2,500 artifacts of animal bones and ivory along with stone tools and evidence of human habitation.

The discovery was published on June 5 as part of a wider study in Nature and shows the Ancient North Siberians endured extreme conditions in the region 31,000 years ago and survived by hunting woolly mammoths, woolly rhinoceroses, and bison. Several publications, such as The New York Times and Science Magazine, also covered the discovery.

Professor Willerslev said: “These people were a significant part of human history, they diversified almost at the same time as the ancestors of modern day Asians and Europeans and it’s likely that at one point they occupied large regions of the northern hemisphere.”

Dr Martin Sikora, of The Lundbeck Foundation Centre for GeoGenetics and first author of the study, added: “They adapted to extreme environments very quickly, and were highly mobile. These findings have changed a lot of what we thought we knew about the population history of north eastern Siberia but also what we know about the history of human migration as a whole.”

Researchers estimate that the population numbers at the site would have been around 40 people with a wider population of around 500. Genetic analysis of the milk teeth revealed the two individuals sequenced showed no evidence of inbreeding which was occurring in the declining Neanderthal populations at the time.

The complex population dynamics during this period and genetic comparisons to other people groups, both ancient and recent, are documented as part of the wider study which analyzed 34 samples of human genomes found in ancient archaeological sites across northern Siberia and central Russia.

Professor Laurent Excoffier from the University of Bern, Switzerland, said: “Remarkably, the Ancient North Siberians people are more closely related to Europeans than Asians and seem to have migrated all the way from Western Eurasia soon after the divergence between Europeans and Asians.”

Scientists found the Ancient North Siberians generated the mosaic genetic make-up of contemporary people who inhabit a vast area across northern Eurasia and the Americas – providing the ‘missing link’ of understanding the genetics of Native American ancestry.

It is widely accepted that humans first made their way to the Americas from Siberia into Alaska via a land bridge spanning the Bering Strait which was submerged at the end of the last Ice Age. The researchers were able to pinpoint some of these ancestors as Asian people groups who mixed with the Ancient North Siberians.

One of the paper’s senior authors, Professor David Meltzer from Southern Methodist University (SMU), explained: “We gained important insight into population isolation and admixture that took place during the depths of the Last Glacial Maximum – the coldest and harshest time of the Ice Age – and ultimately the ancestry of the peoples who would emerge from that time as the ancestors of the indigenous people of the Americas.” Meltzer is an anthropologist at SMU’s Dedman College of Humanities & Sciences.

This discovery was based on the DNA analysis of a 10,000 year-old male remains found at a site near the Kolyma River in Siberia. The individual derives his ancestry from a mixture of Ancient North Siberian DNA and East Asian DNA, which is very similar to that found in Native Americans. It is the first time human remains this closely related to the Native American populations have been discovered outside of the US.

Professor Willerslev added: “The remains are genetically very close to the ancestors of Paleo-Siberian speakers and close to the ancestors of Native Americans. It is an important piece in the puzzle of understanding the ancestry of Native Americans as you can see the Kolyma signature in the Native Americans and Paleo-Siberians. This individual is the missing link of Native American ancestry.” — St. John’s College, University of Cambridge

Read The New York Times article here. More publications on the discovery can be found here:

A 31,000-year-old milk tooth was discovered in this small area among ancient remnants of tools and animal bones. Photo credit: Elena Pavlova

 

About SMU

SMU is the nationally ranked global research university in the dynamic city of Dallas. SMU’s alumni, faculty and nearly 12,000 students in seven degree-granting schools demonstrate an entrepreneurial spirit as they lead change in their professions, communities and the world.

 

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CBS 7: Research shows Permian Basin sinkholes are growing

DALLAS (SMU) – SMU geophysicist Zhong Lu was interviewed by CBS-7’s Shane Battis to discuss the ongoing issue of West Texas sinking.

So far, two large sinkholes have formed near Wink, Texas. But Lu notes that the problem is only expected to get worse over time, due to the Permian Basin in Wink and other neighboring towns having a layer of salt below the ground. In many cases, oil and gas drilling has allowed leaking water to soften that salt layer and cause the surface to cave in, Lu explained.

Lu and fellow SMU geophysicist Jin-Woo Kim have done a series of studies on the phenomenon of the ground sinking at alarming rates in West Texas.  Earlier studies have revealed significant ground movement that suggests the two existing holes are expanding and new ones are forming.

The researchers used satellite radar images that were made public by the European Space Agency, and supplemented that with oil activity data from the Railroad Commission of Texas.

Lu and Kim are both in the SMU’s Roy M. Huffington Department of Earth Sciences, which is part of the Dedman College of Humanities & Sciences.

As Lu told Battis, the deterioration can cause serious problems for people in Wink.

“I think if you live in that area, I would be very concerned,” he said.

For instance, he noted that sinking ground can bend roads into unsafe shapes that put drivers and risk, and it can also damage pipelines underground.

Watch the CBS-7 news segment. 

 

EXCERPT

WINK, Tx. (KOSA) – Research by geophysics has shown the Permian Basin may be booming economically, but it’s also sinking physically.

Wink is known for its massive sinkhole, but new research suggests that in the coming years that sight might not be so uncommon.

It turns out Wink isn’t the only spot prone to sinkholes.

Researchers at Southern Methodist University have found points all over the Permian Basin where the ground is sinking at 5 to 53 centimeters every year.

But why?

CBS7 spoke to a Dr. Zhong Lu, a geophysics professor at SMU who has been studying sinkholes patterns in the Permian Basin.

He explained the Permian Basin has a layer of salt below the ground surface and in many instances oil and gas drilling has allowed leaking water to soften that layer and cause the surface to cave in.

“The casings on the oil wells, it has problems and it cracks and leaks through the casing,” Lu said. “And the corrosion of the metal pipe may also be happening as well that allows the water to diffuse into that area.”

 

About SMU

SMU is the nationally ranked global research university in the dynamic city of Dallas. SMU’s alumni, faculty and nearly 12,000 students in seven degree-granting schools demonstrate an entrepreneurial spirit as they lead change in their professions, communities and the world.