wise vogel P-glycoprotein
Top Quark: New precise particle measurement improves subatomic tool for probing mysteries of universe
Physicists at Southern Methodist University, Dallas have achieved a new precise measurement of a key subatomic particle, opening the door to better understanding some of the deepest mysteries of our universe.
The researchers calculated the new measurement for a critical characteristic — mass — of the Top Quark. The new SMU value confirms recent measurements by other physicists — but adds growing uncertainty to physics’ Standard Model. Continue reading
SMU physiologist and biomechanics researcher Peter G. Weyand contributed a piece on cheating in sports to the U.S. online news magazine and blog the Huffington Post.
The piece addresses how modern cheating controversies in sports indicate the need for a new approach to judge fairness that encompasses a broader range of possibilities. Continue reading
Drugs important in the battle against cancer responded the way they do in real life and behaved according to predictions when tested in a computer-generated model of one of the cell’s key molecular pumps — the protein P-glycoprotein, or P-gp.
The drug-like compounds can be modified and developed into medicines that target a protein in the human body that is responsible for chemotherapy resistance in cancers, said biochemist Pia D. Vogel. Continue reading
A picture is worth 1,000 words when it comes to understanding how things work, but 3D moving pictures are even better. That’s true for scientists trying to stop cancer by better understanding the proteins that make some chemotherapies unsuccessful. Now SMU biochemist John G. Wise at SMU has brought to life in a moving 3D computer model the structure of a key protein related to recurring cancers. Continue reading
They hope to find a compound that can be developed into a drug that re-enables chemotherapy after it fails to work against recurring cancer. Continue reading